| Bioactivity: |
Cyclo(RGDfC) is a cyclic RGD peptide with high binding affinity to alpha(v)beta(3) integrin, a cell-surface receptor that plays a key role in cell adhesion, migration, and signaling pathways. It disrupts integrin-mediated cell-extracellular matrix interactions and has been shown to inhibit pluripotent marker expression in embryonic stem cells as well as reduce tumorigenic potential in vivo. This peptide is widely used in cancer research, angiogenesis studies, and stem cell biology research. |
| Three-letter Sequence: |
cyclo(Arg-Gly-Asp-{d-Phe}-Cys) |
| Appearance: |
White powder |
| Counter Ion: |
TFA salt |
| Storage: |
-20°C / -80°C |
| Reconstitution: |
H2O |
| Shipping: |
All peptides will be shipped as lyophilized powder with desiccant at room temperature. |
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