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Peptide Modifications

Overview

 

NovoPep provides a comprehensive range of high-quality peptide modification services to enhance the stability, bioactivity, solubility, and detectability of your synthetic peptides. Our experienced chemists perform a wide variety of modifications at the N-terminus, C-terminus, or on specific amino acid side chains, utilizing state-of-the-art Fmoc solid-phase peptide synthesis (SPPS) and well-established conjugation chemistries.

 

The price list below covers our most commonly requested peptide modifications. For modifications not listed, or for complex multi-site modified/cyclized/conjugated peptides, please contact us directly for a tailored quotation.

 

Common Modificaitons

 Price(USD)

Fluorescence dyes and FRET

 Price(USD)

Acetylation, N-terminal 

 Free

FITC (fluorescein), N-terminal

 $150

Amide, C-terminal

 Free

FITC, C-terminal or Lys side chain

 $250

Biotin, N-terminal

 $50

Dansyl, N-terminal

 $150

Biotin, C-terminal or Lys side chain

 $150

MCA, N-terminal

 $150

CBZ (Benzyloxycarbonylation)

 1 residue

MCA, N-terminal / Dnp, Lys side chain

 $200

Phosphorylation (Ser, Thr, Tyr)

 $125

Dnp, Lys side chain

 $50

D-amino acid

 $50

Abz, N-terminal

 $150

Myristylation, N-terminal

 $65

Abz/PNBA

 $200

pGlu (pyroglutamate), N-terminal

 $30

EDANS or DABCYL

 $350

   

AMC,, C-termimal

 $125

       

Conjugation

 Price(USD)

Cyclization

 Price(USD)

BSA

 $150

Disulfide bond (1)

 $150

KLH

 $150

Disulfide bond (2)

 $300

OVA

 $150

Disulfide bond (3)

 $1,500

MAP

 $150

Amide bond

 $600

       

Fatty Acid, N-terminal

 Price(USD)

   

Lauric acid

 $65

   

Myristic acid

 $65

   

Palmitic acid

 $65

   

Stearic acid

 $65

   
       

Other Modifications 

 Price(USD)

Other Modifications 

 Price(USD)

4-hydroxyproline

 $50

DTPA, N-terminal

 $275

5-carboxyfluorescein

 $150

EDANS linked to the side chain of E residue

 $350

5'-FAM, N-terminal

 Quote us

FLN

 $125

6-aminohexanoyl

 1aa

Gaba

 Free

7-MethoxyCoumarin, N-terminal

 $200

HEL, C-terminal

 $240

Acetylation, Lys side chain

 $50

Hydroxyproline

 $50

Aha(aminohexanoic acid)

 1aa

HYNIC, N-terminal

 $275

Aib (amino isobutiric acid)

 $75

K(me) mono-methylated Lysine

 $325

Alpha-aminoisobutyric

 $75

K(me)2 di-methylated Lysine

 $175

Aminooxy, N-terminal

 $100

K(me)3 tri-methylated Lysine

 $350

AOAA (amino-oxyacetic acid)

 $75

MAP(4 Branches,<20mg)

 $500

Boc, N-terminal

 Free

NVOC(nitroveratryloxycarbonyl)

 $250

Bpa (p-benzoylphenylalanine)

 $175

Ornithine

 $150

Br (hydrogen) any where

 $20

p-benzoylphenylalanine

 $175

Bromoacetyl

 $175

PNA, (p-Nitroanilide)

 $125

BtLC (6-biotinamidohexanoyl)

 $75

Rhodamine, N-terminal

 $175

C(Npys)

 $75

Stearate(Octadecanoic acid)

 $75

CHO/Formylation, N-terminal

 $80

Succinylation (Suc, N-Terminal)

 $50

CIT(citrulline)

 2 residues

Thioester, C-terminal

 $350

Cys(acm), Cys(tBu)

 $75

Thyroxine (T4)

 $125

 

NovoPep also provides custom stable isotope labeled peptides using 13C/15N residues. These labeled peptides are ideal for quantitative proteomics, mass spectrometry absolute quantification, NMR structural studies and metabolomics research.